大肠癌是我国常见肿瘤,其发病率已位居恶性肿瘤谱的第3—5位,且呈继续上升趋势。我国20多年大肠癌的流行病学研究明确了中国人大肠癌的危险因素为肠息肉史、慢性腹泻、慢性便秘、粘液血便、精神刺激史、饮不洁水史、阑尾手术史和家族肿瘤史等,并在此基础上建立了数量化的评价模式AD值,结合RPHA-FOB为初筛,肠镜为精筛,建立并优化了大肠癌的序贯筛检方案,在人群中应用取得了较好的结果,适合全国推广。同时,以人群为基础,以队列研究和整群随机对照试验的方法,对两个大肠癌现场进行群体防治,从普通人群中检出大肠癌高危人群或癌前病变,对癌前病变腺瘤和息肉进行摘除(即对高危人群进行干预),有效预防了大肠癌的发生并大幅度降低全人群大肠癌死亡率与发病率
s Congress clear risk factors for colorectal cancer history of intestinal polyps, chronic diarrhea, chronic constipation, bloody mucus, stimulate the spirit of history, history of drinking unclean water, and family history of appendectomy surgery tumor History and so on, and on this basis the number of established evaluation model of AD values, combined with RPHA-FOB for screening, colonoscopy screening for sperm to build and optimize a sequential colorectal cancer screening program, the application of the crowd made better results for the whole country. At the same time, population-based, cohort study and a cluster randomized controlled trial of the method, the two groups in the field of colorectal cancer prevention, detection from the general population in high-risk groups of colorectal cancer or precancerous lesions, precancerous lesions of the gland for removal of tumors and polyps (that is, to intervene on the high-risk groups), effectively prevented the occurrence of colorectal cancer and a significant reduction in population-wide colorectal cancer mortality and morbidity
Colorectal cancer is a common tumor in China, the incidence of malignant tumors has been ranked the first 3-5 digital spectrum, and showed an upward trend to continue. Colorectal cancer in China for more than 20 years of epidemiological studies of China's National People'
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